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6-letter words (5 found)
PISSER,PRISES,SPEIRS,SPIERS,SPIRES,
5-letter words (18 found)
EPRIS,PERIS,PIERS,PISES,PRESS,PRIES,PRISE,PRISS,RIPES,RISES,RISPS,SEIRS,SIPES,SIRES,SPEIR,SPIER,SPIES,SPIRE,
4-letter words (25 found)
IRES,PERI,PIER,PIES,PIRS,PISE,PISS,PSIS,REIS,REPS,RIPE,RIPS,RISE,RISP,SEIR,SEIS,SEPS,SERS,SIES,SIPE,SIPS,SIRE,SIRS,SPIE,SRIS,
3-letter words (20 found)
ERS,ESS,IRE,PER,PES,PIE,PIR,PIS,PRE,PSI,REI,REP,RES,RIP,SEI,SER,SIP,SIR,SIS,SRI,
2-letter words (7 found)
ER,ES,IS,PE,PI,RE,SI,
1-letter words (1 found)
E,
You can make 76 words from spiers according to the Scrabble US and Canada dictionary.