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8-letter words (1 found)
LOUSIEST,
7-letter words (5 found)
LOTUSES,OUTLIES,SOLUTES,SOUTIES,TOUSLES,
6-letter words (30 found)
EUSOLS,ISLETS,ISTLES,LOUIES,LOUSES,OUSELS,OUTLIE,SETOUS,SLIEST,SLUITS,SOLEUS,SOLUTE,SOUTIE,STEILS,STILES,STOLES,SUITES,SUTILE,TISSUE,TOILES,TOISES,TOUSES,TOUSLE,TUILES,TULSIS,TUSSLE,ULOSES,ULOSIS,UTILES,UTISES,
5-letter words (65 found)
ETUIS,EUSOL,ILEUS,ISLES,ISLET,ISSUE,ISTLE,LESTS,LIEUS,LISTS,LITES,LOESS,LOSES,LOTES,LOTUS,LOUIE,LOUIS,LOUSE,LOUTS,LUSTS,LUTES,OUSEL,OUSTS,SEILS,SILES,SILOS,SILTS,SITES,SITUS,SLITS,SLOES,SLOTS,SLUES,SLUIT,SLUSE,SLUTS,SOILS,SOLEI,SOLES,SOLUS,SOULS,SOUSE,SOUTS,STEIL,STIES,STILE,STOLE,SUETS,SUITE,SUITS,TEILS,TELOI,TELOS,TILES,TOILE,TOILS,TOISE,TOLES,TOLUS,TOSES,TOUSE,TUILE,TULES,TULSI,UTILE,
4-letter words (78 found)
ELTS,ESTS,ETUI,EUOI,ISLE,ISOS,LEIS,LESS,LEST,LETS,LIES,LIEU,LIST,LITE,LITS,LITU,LOSE,LOSS,LOST,LOTE,LOTI,LOTS,LOUS,LOUT,LUES,LUIT,LUST,LUTE,OILS,OLES,OSES,OUST,OUTS,SEIL,SEIS,SELS,SETS,SIES,SILE,SILO,SILT,SIST,SITE,SITS,SLIT,SLOE,SLOT,SLUE,SLUT,SOIL,SOLE,SOLI,SOLS,SOTS,SOUL,SOUS,SOUT,STIE,SUES,SUET,SUIT,TEIL,TELS,TIES,TILE,TILS,TOES,TOIL,TOLE,TOLU,TOSE,TOSS,TUIS,TULE,ULES,USES,UTES,UTIS,
3-letter words (47 found)
ELS,ELT,ESS,EST,IOS,ISO,ITS,LEI,LES,LET,LEU,LIE,LIS,LIT,LOS,LOT,LOU,OES,OIL,OIS,OLE,OSE,OUS,OUT,SEI,SEL,SET,SIS,SIT,SOL,SOS,SOT,SOU,SUE,SUI,SUS,TEL,TES,TIE,TIL,TIS,TOE,TUI,ULE,USE,UTE,UTS,
2-letter words (20 found)
EL,ES,ET,IO,IS,IT,LI,LO,OE,OI,OS,OU,SI,SO,ST,TE,TI,TO,US,UT,
1-letter words (1 found)
E,
You can make 247 words from lousiest according to the Scrabble US and Canada dictionary.