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10-letter words (1 found)
OPTIMISTIC,
8-letter words (2 found)
OPTICIST,OPTIMIST,
7-letter words (4 found)
MIOTICS,MISTICO,MITOTIC,SOMITIC,
6-letter words (13 found)
COMPTS,IMPOST,IMPOTS,MIOTIC,OPTICS,OTITIC,OTITIS,PICOTS,PITOTS,PTOTIC,SITCOM,TIMIST,TOPICS,
5-letter words (31 found)
COITS,COMPS,COMPT,COTTS,IMPIS,IMPOT,MICOS,MITIS,MITTS,MOIST,MOITS,MOTIS,MOTTS,OMITS,OPTIC,OSMIC,PICOT,PISCO,PITOT,POSIT,POTTS,STOIC,STOIT,STOMP,STOPT,TIMPS,TIPIS,TITIS,TOITS,TOPIC,TOPIS,
4-letter words (62 found)
CIST,CITO,CITS,COIT,COMP,COMS,COPS,COST,COTS,COTT,IMPI,IMPS,ISIT,MICO,MICS,MIPS,MISO,MIST,MITT,MOCS,MOIT,MOPS,MOST,MOTI,MOTS,MOTT,OMIT,OPTS,OTIC,PICS,PISO,PITS,POIS,POMS,POST,POTS,POTT,SCOP,SCOT,SIMI,SIMP,SMIT,SPIC,SPIM,SPIT,SPOT,STIM,STOP,STOT,TICS,TIPI,TIPS,TIPT,TITI,TITS,TOCS,TOIT,TOMS,TOPI,TOPS,TOST,TOTS,
3-letter words (46 found)
CIS,CIT,COP,COS,COT,IMP,IOS,ISM,ISO,ITS,MIC,MIS,MOC,MOI,MOP,MOS,MOT,OIS,OMS,OPS,OPT,PIC,PIS,PIT,POI,POM,POS,POT,PSI,PST,SIC,SIM,SIP,SIT,SOC,SOM,SOP,SOT,TIC,TIP,TIS,TIT,TOC,TOM,TOP,TOT,
2-letter words (16 found)
IO,IS,IT,MI,MO,OI,OM,OP,OS,PI,PO,SI,SO,ST,TI,TO,
You can make 175 words from optimistic according to the Scrabble US and Canada dictionary.