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7-letter words (1 found)
WISEGUY,
5-letter words (2 found)
GUISE,GUYSE,
4-letter words (14 found)
EGIS,GIES,GUES,GUYS,SWEY,SWIG,UEYS,WEYS,WIGS,WISE,WYES,YEWS,YUGS,YWIS,
3-letter words (28 found)
GEY,GIE,GIS,GUE,GUS,GUY,SEG,SEI,SEW,SEY,SIG,SUE,SUG,SUI,SWY,SYE,UEY,UGS,USE,WEY,WIG,WIS,WUS,WYE,YES,YEW,YUG,YUS,
2-letter words (11 found)
ES,EW,GI,GU,IS,SI,UG,US,WE,YE,YU,
1-letter words (1 found)
E,
You can make 57 words from wiseguy according to the Scrabble US and Canada dictionary.