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8-letter words (1 found)
WISEGUYS,
7-letter words (1 found)
WISEGUY,
6-letter words (3 found)
GUISES,GUSSIE,GUYSES,
5-letter words (11 found)
GUESS,GUISE,GUSSY,GUYSE,ISSUE,SWEYS,SWIES,SWIGS,WISES,WUSES,WUSSY,
4-letter words (26 found)
EGIS,GIES,GUES,GUYS,SEGS,SEIS,SEWS,SEYS,SIES,SIGS,SUES,SUGS,SWEY,SWIG,SYES,UEYS,USES,WEYS,WIGS,WISE,WISS,WUSS,WYES,YEWS,YUGS,YWIS,
3-letter words (31 found)
ESS,GEY,GIE,GIS,GUE,GUS,GUY,SEG,SEI,SEW,SEY,SIG,SIS,SUE,SUG,SUI,SUS,SWY,SYE,UEY,UGS,USE,WEY,WIG,WIS,WUS,WYE,YES,YEW,YUG,YUS,
2-letter words (11 found)
ES,EW,GI,GU,IS,SI,UG,US,WE,YE,YU,
1-letter words (1 found)
E,
You can make 85 words from wiseguys according to the Scrabble US and Canada dictionary.