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6-letter words (3 found)
OPUSES,POUSSE,SPOUSE,
5-letter words (9 found)
PESOS,POSES,POSSE,PUSES,SOUPS,SOUSE,SPEOS,SPUES,SUPES,
4-letter words (18 found)
EPOS,OPES,OPUS,OSES,OUPS,PESO,POSE,POSS,PUSS,SEPS,SOPS,SOUP,SOUS,SPUE,SUES,SUPE,SUPS,USES,
3-letter words (19 found)
ESS,OES,OPE,OPS,OSE,OUP,OUS,PES,POS,PUS,SOP,SOS,SOU,SUE,SUP,SUS,UPO,UPS,USE,
2-letter words (10 found)
ES,OE,OP,OS,OU,PE,PO,SO,UP,US,
1-letter words (1 found)
E,
You can make 60 words from spouse according to the Scrabble US and Canada dictionary.