You can make 181 valid words from the letters in ACEKLMPU using the Scrabble US/CAN dictionary.
How many points is ACEKLMPU worth in Scrabble?
ACEKLMPU is worth 18 points in Scrabble (US/CAN) and 23 points in Words With Friends.
How do I use the Word Unscrambler tool?
Enter any letters into the input box and press Search. The tool will return every valid English word that can be made from those letters using the dictionary you select.