You can make 172 valid words from the letters in DEFIIMRS using the Scrabble US/CAN dictionary.
How many points is DEFIIMRS worth in Scrabble?
DEFIIMRS is worth 14 points in Scrabble (US/CAN) and 15 points in Words With Friends.
How do I use the Word Unscrambler tool?
Enter any letters into the input box and press Search. The tool will return every valid English word that can be made from those letters using the dictionary you select.