You can make 272 valid words from the letters in DENOPRSV using the Scrabble US/CAN dictionary.
How many points is DENOPRSV worth in Scrabble?
DENOPRSV is worth 14 points in Scrabble (US/CAN) and 17 points in Words With Friends.
How do I use the Word Unscrambler tool?
Enter any letters into the input box and press Search. The tool will return every valid English word that can be made from those letters using the dictionary you select.